Research Interest

Pharmacodynamics of autonomic and cardiovascular agents. Toxicology of natural toxins including the arrow poisons of plant origin. Medico-legal issues involving litigation in court and editorial work for Cellular and Molecular Biology an international journal.

Recent Publications

1. Ochillo, R.F., S.T. Kau and B.V. Sastry (1977). Nicotinic Activities of 5-methylfurfuryltrimettrylammonium iodide, an analogy of muscarine. Pharmacological Res. Comm., 9:719-727.
2. Ochillo, R.F., P.P. Rowell and B.V.R. Sastry (1977). Effects of cooling on the levels of acetylcholine, cholinesterase, choline acetyltransferase and the intramural electrical stimulations of the guinea pig ileum. Pharmacology,16:122-130.
3. Ochillo, R.F., A.K. Chaturvedi and B.V.R. Sastry (1980). Toxicological and pharmacological effects of furan analogs of muscarine. Tox. Applied Pharmacology,43: 73-83.
4. Ochillo, R.F (1981). Apparent activity of 5-methylfurmethide at muscarinic receptors. Arch. Int. Pharmacodyn. , 248:69-75.
5. Ochillo, R.F., C.S Tsai and M.H. Tsai (1981). Mechanism of action of muscarine on the longitudinal muscle of the guinea pig isolated ileum. British Journal Pharmacology,72: 225-232.
6. Cook, E.B., M. Dennis and R. F. Ochillo (1981). Application of thin layer, ion exchange and high performance liquid chromatography to separate pharmacologically active components of an African arrow poison of plant origin. J. Liq. Chrom., A(3):549-557.
7. Dennis, M and R.F. Ochillo (1981). Selection of a suitable solvent system for the isolation of toxicologically active components of an African arrow poison of plant origin. J. Liq. Chrom., 4(10):1847-1854.
8. Ochillo, R.F. and C.S Tsai (1982). Influence of verapamil on the frequency and amplitude of cholinergic-initiated spontaneous contractions of gastric muscularis muscle of Bufo marinus.Pharmacology, 24:185-192.
9. Ochillo, R.F. and C.S Tsai (1982). The effects of indomethacin and prostaglandin E2 on the cholinergic initiated contractions of gastric muscularis muscle of Bufo marinus. Arch. Int. Pharmacodyn.,257:105-113.
10. Tsai, C.S. and R.F. Ochillo (1983). Preliminary pharmacological characterization of the isolated circular strips of gastric muscularis muscle of Bufo marinus: a new preparation. J. Pharmocol. Methods, 20: 45-53.
11. Tsai, C.S. and R. F. Ochillo (1985). Comparative studies of cardiovascular effects of a new dopamine agonist (SK $ F 3839A) and dopamine. Gen. Pharmol., 16:85-89.
12. Tsai, C.S. and R.F. Ochillo (1986). The influence of prostaglandins E2 on the acetylcholine-initiated contractions of isolated gastric muscularis muscle of Bufo marinus.Comp. Biochem. Physiol., 83C: 211-215.
13. Ochillo, R.F. and C.S Tsai (1986). Temperature and smooth muscle automaticity. In Living in The Cold: “Physiological and Biochemical Adaptations”. (Eds. H.C. Helle, X.J. Musacchia and L.C.H. Wang). Elsevier Publishing Comp. New York, N. Y.
14. Bui, K. and R.F. Ochillo (1986). Characterization of cholinesterase of muscularis muscle of Bufo marinus.Comp. Biochem. Physiol.,87C: 107-111.
15. Tsai, C.S. and R.F. Ochillo (1988). The effects of hypothermia on the blockade of muscarinic receptors by phenoxybenzamine. Arch. Int. Pharmoacodyn. Therapy,292:76-85.
16. Tsai, C.S. and R.F. Ochillo (1989). Low temperature and muscarinic receptor activity. Cryobiology. 26(5): 485-493.
17. Tsai, C.S., C. Washington and R.F. Ochillo (1990). Cardiovascular effects of doxorubicin. Gen. Pharmol.,21(5): 729-933.
18. Sastry, B.V.R., L.K. Owens and R.F. Ochillo (1990). Two furan analogs of muscarine as selective agonists at the presynaptic muscarinic receptors of the guinea pig longitudinal muscle. In presynaptic receptors and the question of autoregulation of neurotransmitter release. Ann. New York Acad. Science,604:566-568.
19. Ochillo, R.F (1991). A working hypothesis of acute stress-induced hypotension. Medical Hypothesis., 36: 179-180.
20. Tsai, C.S. and R. F. Ochillo (1991). The pharmacological effects of berberine on the isolated longitudinal muscle of guinea-pig ileum. Arch. Int. Pharmacodyn. Therapy. 310:116-130.
21. Washington, B., M.O. Smith, T.J. Robinson and R.F. Ochillo (1991). A rapid qualitative and quantitative method for the assay of histamine in small volume of plasma. J. Liq. Chromar., 14(11): 2189-2200; 1991.
22. Washington, B., M.O. Smith, T.J. Robinson and R. F. Ochillo (1992). Selection of a suitable solvent system for the quantitation of histamine in small volume plasma samples. J. Liq. Chrom., 14(7): 1417 –1424.
23. Washington, B. M. O. Smith, K. Nguyeu and R. F. Ochillo (1993). Application of a novel technique: the determination of histamine content of urine, brain and cerebral spinal fluid. . J. Liq. Chrom., 16(5): 1195-1208,1993.
24. Guede-Guina F, C. S. Tsai, M.O. Smith, M. Vangah-Manda, B. Washington and R. F. Ochillo (1995). The use of isolated functional heart to pharmacologically characterize active ingredients in aqueous extracts of Mareya micrantha.J. Ethnopharmacology,45:19-26,1995.
25. Tsai, C. S., F. Guede-Guina, M. O. Smith, M. Vangah-Manda, and R. F. Ochillo (1995). Isolation of cholinergic active ingredients in aqueous extracts of Mareya micrantha using the longitudinal muscle of the isolated guinea-pig ileum as a pharmacological activity marker. K. Ethnophaacology, 45:215-222.
26. Hughes C. A., T. D. Adams, M. C. Jenkins, T. J. Robinson and R. F. Ochillo (1996). Differential expression of the protein kinase c family of isocymes in synaptosomes from brains of rats stressed by sleep deprivation. Cell. Mol. Biol., 42:40.
27. Hughes-Darden C. A., S. J. Wachira, E. Batta, R. F. Ochillo and T. J. Robinson (2001). Effects of gamma-2-meanocyte- stimulating hormone on protein kinase c activity and expression in spontaneous hypertensive rats. Cell. Mol. Biol., 47(6) 069-1075.
28. Ochillo R. F (1997). Message from the editor. Cell Mol. Biology,43(7), iii-iv.
29. Ochillo, R. F., T. J. Robinson, S.A. McNairy and S.A. McLure (2003). Research Centers in Minority Institutions. Cell. Mol. Biol., 49(8): 1183-1186,2003.
30. Ochillo R. F (2004). Editorial in honor of Sir Francis Crick. Cell Mol. Biol., 50(6): 669.